ISH Protease 3

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DIAGNOSTICS F. Hoffmann-La Roche Ltd

ISH Protease 3

Catalog Number:780-4149
Ordering Code:05273331001
Quantity:200 tests

Ventana Medical Systems, Inc. (Ventana) ISH Protease 3 is an endopeptidase of the serine protease family, which is nonspecific and cleaves all peptide bonds. ISH Protease 3 is a low activity enzyme formulation relative to the stronger ISH Protease 2. ISH Protease 3 is used in the in situ hybridization process to remove protein that surrounds the target DNA or RNA sequences of interest. The incubation time and temperature have been carefully optimized by probe type on the BenchMark or BenchMark XT automated slide stainer to prevent disruption of tissue or cellular integrity. Light microscopy is used to detect the staining reaction. Positive results aid in the classification of normal and abnormal specimens, and serve as an adjunct to conventional histopathology or cytopathology tests. The clinical interpretation of any staining, or the absence of staining, must be complemented by morphological studies and evaluation of proper controls. Evaluation must be made by a qualified pathologist within the context of the patient’s clinical history and other diagnostic tests. This reagent is intended for in vitro diagnostic (IVD) use.

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