Collagen Type IV (CIV22)

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DIAGNOSTICS F. Hoffmann-La Roche Ltd

Collagen Type IV (CIV22)

Collagen Type IV (CIV22), kidney, 200x
Catalog Number:760-2632
Ordering Code:05267439001
Quantity:50 tests
Controls:Lung, Muscle
Clone Name:CIV22
Localization:Basement Membrane
Regulatory Status:IVD

Collagen Type IV is the major component of the basal lamina so antibodies to this molecule confirm its presence and reveal the morphological appearance of the structure. Normal tissue stains with this antibody in a fashion consistent with the sites of mesenchymal elements and epithelial basal laminae. Anti-Collagen IV can also be useful in the classification of soft tissue tumors; schwanomas, leiomyomas. Their well differentiated, malignant counterparts usually immunoreact with this antibody. The vascular nature of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma can be revealed by this antibody with greater reliability than non-specific stains (e.g. silver reticulum).