Granzyme B (polyclonal)

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DIAGNOSTICS F. Hoffmann-La Roche Ltd

Granzyme B (polyclonal)

Granzyme B (polyclonal), spleen, 100x
Catalog Number:760-4283
Ordering Code:05269466001
Quantity:50 tests
Clone Name:Polyclonal
Localization:Granular 2, Cytotoxic Thymphocytes, Natural Killer Cells
Regulatory Status:IVD

Granzymes are serine proteases which are stored in specialized lytic granules of cytotoxic T lymphocytes and in natural killer cells. Anti-Granzyme B has been useful in diagnosing Natural killer/T cell lymphoma, as well as anaplastic large cell lymphoma. High percentages of cytotoxic T cells have been shown to be an unfavorable prognostic indicator in Hodgkin's disease.